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Paolo Curatolo Selected Research

Epilepsy (Aura)

11/2023Molecular EPISTOP, a comprehensive multi-omic analysis of blood from Tuberous Sclerosis Complex infants age birth to two years.
11/2023Updated clinical recommendations for the management of tuberous sclerosis complex associated epilepsy.
10/2023Is tuberous sclerosis complex-associated autism a preventable and treatable disorder?
10/2023Updated Genotype-Phenotype Correlations in TSC.
1/2023Epileptogenesis in tuberous sclerosis complex-related developmental and epileptic encephalopathy.
7/2022miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex.
3/2022Current role of surgery for tuberous sclerosis complex-associated epilepsy.
1/2022Association of Early MRI Characteristics With Subsequent Epilepsy and Neurodevelopmental Outcomes in Children With Tuberous Sclerosis Complex.
1/2022Questionnaire-based assessment of sleep disorders in an adult population of Tuberous Sclerosis Complex.
1/2022Genetic pathogenesis of the epileptogenic lesions in Tuberous Sclerosis Complex: Therapeutic targeting of the mTOR pathway.
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Paolo Curatolo Research Topics

Disease

83Tuberous Sclerosis (Bourneville's Disease)
11/2023 - 01/2006
60Epilepsy (Aura)
11/2023 - 01/2008
47Seizures (Absence Seizure)
11/2023 - 04/2005
22Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
12/2022 - 12/2006
20Autism Spectrum Disorder
10/2023 - 12/2010
17Autistic Disorder (Autism)
10/2023 - 03/2007
16Astrocytoma (Pilocytic Astrocytoma)
01/2019 - 12/2012
14Inborn Genetic Diseases (Disease, Hereditary)
10/2023 - 02/2009
12Angiomyolipoma
01/2020 - 06/2008
9Intellectual Disability (Idiocy)
10/2023 - 09/2006
9Infantile Spasms (West Syndrome)
01/2023 - 04/2006
9Drug Resistant Epilepsy
01/2022 - 02/2009
7Brain Diseases (Brain Disorder)
11/2023 - 02/2009
7Neoplasms (Cancer)
01/2021 - 08/2011
6Neurodevelopmental Disorders
10/2021 - 12/2012
5Lennox Gastaut Syndrome
01/2023 - 11/2010
5Lymphangioleiomyomatosis (Lymphangiomyomatosis)
01/2019 - 09/2013
4Hamartoma
01/2018 - 08/2011
4Hydrocephalus (Hydrocephaly)
01/2017 - 01/2011
3Tics (Tic)
02/2022 - 12/2006
3Tourette Syndrome (Tourette's Syndrome)
02/2022 - 12/2006
3Sleep Wake Disorders
01/2022 - 02/2020
3Focal Cortical Dysplasia
11/2021 - 11/2007
3Headache (Headaches)
05/2021 - 05/2006
3Epileptic Syndromes
01/2021 - 06/2010
3Cognitive Dysfunction
10/2020 - 07/2004
3Rett Syndrome (Rett's Disorder)
01/2020 - 02/2017
3Rhabdomyoma
01/2017 - 09/2013
3Abdominal Pain (Pain, Abdominal)
01/2015 - 09/2009
3Absence Epilepsy (Childhood Absence Epilepsy)
03/2014 - 11/2008
3Partial Epilepsies (Epilepsy, Partial)
12/2013 - 02/2009
3Oppositional Defiant Disorder
11/2009 - 12/2006
2Spasm (Spasms)
11/2023 - 11/2007
2Anxiety Disorders (Anxiety Disorder)
02/2022 - 11/2019
2Rare Diseases (Rare Disease)
01/2021 - 11/2014
2Skin Manifestations
09/2013 - 12/2012
2Syncope (Fainting)
05/2011 - 11/2010
2Rolandic Epilepsy (Centrotemporal Epilepsy)
06/2010 - 07/2004
2Juvenile Myoclonic Epilepsy
06/2010 - 01/2008
2Cerebral Palsy (Spastic Diplegia)
06/2010 - 02/2007
2Down Syndrome (Down's Syndrome)
08/2004 - 11/2003
1Learning Disabilities (Learning Disability)
12/2022
1Neurocutaneous Syndromes (Phakomatoses)
03/2022
1Tic Disorders (Tic Disorder)
02/2022
1Sleepiness
01/2022
1Hemimegalencephaly
11/2021
1Sclerosis
11/2021
1Language Development Disorders (Semantic-Pragmatic Disorder)
01/2021
1Specific Language Disorder
01/2021
1Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis)
01/2021
1Disease Progression
01/2021

Drug/Important Bio-Agent (IBA)

74trans-sodium crocetinate (crocetin)IBA
11/2023 - 01/2006
26EverolimusFDA Link
11/2023 - 08/2011
19Anticonvulsants (Antiepileptic Drugs)IBA
01/2021 - 04/2005
16VigabatrinFDA Link
11/2023 - 04/2006
14Biomarkers (Surrogate Marker)IBA
11/2023 - 08/2009
13TOR Serine-Threonine KinasesIBA
10/2023 - 01/2013
11MTOR InhibitorsIBA
01/2022 - 11/2010
8Sirolimus (Rapamycin)FDA Link
01/2022 - 02/2009
8Methylphenidate (Ritalin)FDA LinkGeneric
10/2018 - 07/2009
7rufinamideFDA Link
01/2018 - 11/2010
6Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric
01/2015 - 07/2009
5Proteins (Proteins, Gene)FDA Link
10/2020 - 09/2006
5Levetiracetam (Keppra)FDA LinkGeneric
03/2014 - 01/2008
4Topiramate (Topamax)FDA LinkGeneric
01/2018 - 05/2006
4Serotonin (5 Hydroxytryptamine)IBA
03/2011 - 03/2007
3MelatoninIBA
05/2021 - 03/2015
3Tryptophan (L-Tryptophan)FDA Link
05/2021 - 02/2020
3Valproic Acid (Depakote)FDA LinkGeneric
01/2018 - 06/2013
3Retinaldehyde (Retinal)IBA
01/2018 - 04/2014
2CannabidiolIBA
11/2023 - 12/2018
2CytokinesIBA
11/2022 - 01/2019
2Vitamin B 6IBA
02/2022 - 02/2020
2Mechanistic Target of Rapamycin Complex 1IBA
10/2021 - 01/2017
2arylesteraseIBA
01/2021 - 12/2010
2gamma-Aminobutyric Acid (GABA)IBA
03/2019 - 11/2007
2lipoarabinomannan (LAM)IBA
01/2019 - 01/2018
2DNA (Deoxyribonucleic Acid)IBA
01/2019 - 01/2012
2Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
02/2018 - 01/2015
2perampanelIBA
01/2018 - 06/2017
2Oxcarbazepine (Trileptal)FDA LinkGeneric
01/2018 - 06/2013
2Phenobarbital (Luminal)FDA Link
01/2018 - 06/2012
2Lamotrigine (Lamictal)FDA LinkGeneric
03/2014 - 07/2004
2Antipsychotic Agents (Antipsychotics)IBA
09/2013 - 02/2013
1SandIBA
11/2023
1gamma-Linolenic AcidIBA
12/2022
1Food Additives (Food Additive)IBA
12/2022
1Fatty Acids (Saturated Fatty Acids)IBA
12/2022
1Eicosapentaenoic AcidIBA
12/2022
1Docosahexaenoic AcidsIBA
12/2022
1MicroRNAs (MicroRNA)IBA
07/2022
1theanineIBA
02/2022
1Cell Adhesion MoleculesIBA
01/2022
1Vitamin B Complex (B Vitamins)IBA
05/2021
1MagnesiumIBA
05/2021
1SteroidsIBA
01/2021

Therapy/Procedure

31Therapeutics
10/2023 - 05/2006
8Drug Therapy (Chemotherapy)
01/2022 - 01/2009
2Cesarean Section (Caesarean Section)
06/2014 - 02/2007
1Treatment Delay
01/2021